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The most detailed 3-D picture yet has been created of a membrane protein linked to learning, memory, anxiety, pain and brain disorders such as schizophrenia, Parkinson's, Alzheimer's and autism. The mGlu1 receptor, which helps regulate the neurotransmitter glutamate, belongs to a superfamily of molecules known as G protein-coupled receptors (GPCRs). GPCRs sit in the cell membrane and sense various molecules outside the cell, including odors, hormones, neurotransmitters and light. After binding t...
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